吕志华 个人简介: 吕志华,女,1966年生,博士,教授,博导。现任医药学院副院长,海洋药物教育部重点实验室常务副主任,《中国海洋药物》杂志编辑部主任。 主要从事药物分析与药代动力学教学与研究工作;主讲本科生《现代仪器分析》和研究生《药物色谱分析》课程。 近年以来,先后主持完成国家海洋_ldquo;863_rdquo;计划、参与国家_ldquo;973_rdquo;计划、国家自然科学基金、山东省和青岛市科技计划等课题10余项。目前主持国家自然科学基金1项、参与国家海洋局公益专项1项。发表相关研究论文40余篇。 联系方式:电话:(0532)82032064;E-mail:lvzhihua@ouc.edu.cn 研究生招生与培养: 招收研究生专业:药物化学、制药工程。 已培养硕士研究生17名,目前在读硕士研究生12名,在读博士研究生3名。 研究方向及内容: 1.药物分析新技术和新方法研究; 2.药品质量标准及稳定性研究; 3.体内外药物代谢及其动力学分析。 承担主要课题: 1.活性多糖口服吸收以及转运代谢机制研究(31171665),国家自然科学基金,62万元,2012-2015年,项目负责人。 2.海洋功能寡糖及其药物工程技术开发(编号:201005024),国家海洋局公益专项,2010-2015年,项目总经费926万,参与。 3.抗心脑血管疾病海洋药物研究开发,国家863计划重点项目(2006AA0904),1000万元,2006-2010年,项目牵头人。 4.I类抗动脉粥样硬化新药916的临床研究(2002A,624020),国家863项目,200万元,2002-2005年,项目负责人。 5.I类抗动脉粥样硬化新药916的临床及产业化研究(05-2-HY-49),青岛市科技攻关项目,10万元,2005-2007年,项目负责人。 代表论文: 1. WEN-HUI ZHANG,ZHI-HUALV*, TING-FU JIANG*, YUAN-HONG WANG, LI-PING GUO. Screening Tyrosinase Inhibitors from Traditional Chinese Medicine by Capillary Electrophoresis with Electrophoretically Mediated Microanalysis. Journal of Food and Drug Analysis, 2012, 20 (1): 159-163. 2.TING-FU JIANG*,ZHI-HUALV, XIAO-YAN CUI AND YUAN-HONG WANG.. Analysis of Malachite Green, Gentian Violet and Their Leuco Metabolites in Catfish and Carp by Micellar Electrokinetic Capillary Chromatography. Journal of Food and Drug Analysis, 2012, 20 (1): 94-100. 3Ting-Fu Jiang*,Zhi-Hua Lv*,Yuan-Hong Wang, Mei-E Yue, and Jia-Huan Peng. On-Line Concentration by Field-Enhanced Sample Injection with Reverse Migrating Micelles in Micellar Electrokinetic Capillary Chromatography for the Analysis of Triterpenoids from Traditional Chinese Medicine. Journal of Analytical Chemistry, 2010, 65: 945_ndash;950. 4. Ting-Fu Jiang*,Zhi-Hua Lv, Yuan-Hong Wang and Mei-E Yue. On-line concentration by field-enhanced sample injection with reverse migrating micelles in micellar electrokinetic capillary chromatography for the analysis of coumarins from traditional Chinese medicine and human serum. Biomed. Chromatogr., 2010, 24: 581-587. 5. Li-Ping. Guo, Ting-Fu Jiang,Zhi-Hua. Lv*, Yuan-Hong. Wang. Screening _alpha;-glucosidase inhibitors from traditional Chinese drugs by capillary electrophoresis with electrophoretically mediated microanalysis. J. Pharma. Biomed. Anal., 2010, 53: 1250_ndash;1253. 6.Ting-Fu JIANG*,Zhi-HuaLV, Yuan-Hong WANG, Mei-E YUE, and Shuai LIAN.Separation and Determination of Nitrofuran Antibioticsin Turbot Fish by Microemulsion Electrokinetic Chromatography. Analytical Sciences, 2009, 25: 861-864. 7. Zhi Yang,Zhi-hua Lv*, Ting-Fu Jiang, Yuan-Hong Wang. Affinity CE Determination of the Binding Constant of Bioactive Sulfated Polysaccharide 916 to Human Serum Albumin. Chromatographia, 2009, 70, 475_ndash;479. 8. Yuhong Han,Zhihua Lv*, Tingfu Jiang, Yuanhong Wang, Bioanalysis and pharmacokinetics of chitosan ester in rabbit serum by HPLC with postcolumn fluorescence derivatization. Journal of ChromatographyB, 2007,845:138-142. 9. HanYao,Lv Zhihua*, Tingfu Jiang, Yuanhong Wang, Application of Electrospray Ionization-Collision Induced Dissociation- Tandem Mass Spectrometry in Differentiation Isomers of Human Milk Oligosaccharides. Chinese Journal of Analytical Chemistry. 2006,34: 1213-1218 10.Zhihua Lv*, Yan Sun, Yuanhong Wang, Tingfu Jiang, Guangli Yu, Ultrasensitive Capillary Electrophoresis of Oligoguluronates with Laser-Induced Fluorescence Detection. Chromatographia. 2005, 61(11): 615-618 药物分析新技术和新方法研究;药品质量标准及稳定性研究;体内外药物代谢及其动力学分析 [海洋信息资源服务平台] → 中国 → 山东 → 青岛 海洋生物医药业;海洋药物原药制造; 中国海洋大学 博士学位 2018-09-28 21:48:52