张玲玲 姓名：张玲玲 学历/职称/职务：教授 邮箱：lingling80@ouc.edu.cn 电话：0532-82031969 地址：青岛市鱼山路5号中国海洋大学海洋生命学院 科研领域描述： 研究方向主要集中在海洋贝类功能基因组学领域，通过基因组学、转录组学、基因网络等技术，鉴别和验证扇贝性别决定、繁殖调控、免疫抗逆等相关的关键调控基因，阐明这些基因的表达调控机制。 代表性成果：（*表示通讯作者，#表示共同第一） Li Y,Zhang L*, Sun Y, Ma X, Wang J, Li R, Zhang M, Wang S, Hu X, Bao Z. (2016) Transcriptome sequencing and comparative analysis of ovary and testis identifies potential key sex-related genes and pathways in scallopPatinopecten yessoensis.Marine Biotechnology. 18:453-465. Xing Q, Li Y, Guo H, Yu Q, Huang X, Wang S, Hu X,Zhang L*, Bao Z. (2016) Cardiac performance: a thermal tolerance indicator in scallops.Marine Biology.163:244. Sun Y,Zhang L*, Zhang M, Li R, Li Y, Hu X, Wang S, Bao Z. (2016) Characterization of three mitogen-activated protein kinases (MAPK) genes reveals involvement of ERK and JNK, not p38 in defense against bacterial infection in Yesso scallopPatinopecten yessoensis.Fish _amp; Shellfish Immunology.54: 507-515. Xing Q, Yu Q, Dou H, Wang J, Li R, Ning X, Wang R*, Wang S,Zhang L*, Hu X, Bao Z. (2016) Genome-wide identification, characterization and expression analyses of two TNFRs in Yesso scallop (Patinopecten yessoensis) provide insight into the disparity of responses to bacterial infections and heat stress in bivalves.Fish _amp; Shellfish Immunology.52: 44-56. Wang S#, Lv J#,Zhang L#, Dou J, Sun Y, Li X, Fu X, Dou H, Mao J, Hu X _amp; Bao Z*. (2015) MethylRAD: a simple and scalable method for genome-wide DNA methylation profiling using methylation-dependent restriction enzymes.Open Biology. 5: 150130. Li R, Zhang R, Zhang L, Zou J, Xing Q, Dou H, Hu X,Zhang L*, Wang R*, Bao Z. (2015) Characterizations and expression analyses of NF-_kappa;B and Rel genes in the Yesso scallop (Patinopecten yessoensis) suggest specific response patterns against Gram-negative infection in bivalves.Fish _amp; Shellfish Immunology. 44:611-21. Fu X#, Sun Y#, Wang J, Xing Q, Zou J, Li R, Wang Z, Wang S, Hu X,Zhang L*, Bao Z*. (2014) Sequencing-based gene network analysis provides a core set of gene resource for understanding thermal adaptation in Zhikong scallopChlamys farreri.Molecular Ecology Resources. 14: 184-198. Sun Y, Zhang Y, Fu X, Zhang R, Zou J, Wang S, Hu X,Zhang L*_amp; Bao Z. (2014) Identification of two secreted ferritin subunits involved in immune defense of Yesso scallopPatinopecten yessoensis.Fish _amp; Shellfish Immunology. 37: 53-59. Sun Y, Hou R, Fu X, Changsen Sun, Wang S, Wang C, Li N,Zhang L*_amp; Bao Z. (2014) Genome-wide analysis of DNA methylation in five tissues of Zhikong scallop,Chlamys farreri.PLoS ONE.9: e86232. Zhang Y, Zhang R, Zou J, Hu X, Wang S,Zhang L*, Bao Z*. (2013) Identification and characterization of four ferritin subunits involved in immune defense of the Yesso scallop (Patinopecten yessoensis).Fish _amp; Shellfish Immunology. 34: 1178-1187. Zhang L, Hou R, Su H, Hu X, Wang S* _amp; Bao Z*. (2012) Network analysis of oyster transcriptome revealed a cascade of cellular responses during recovery after heat shock.PLoS ONE.7(4): e35484. Ponomarev I*, Wang S,Zhang L, Harris RA _amp; Mayfield RD*. (2012) Gene co-expression networks in human brain identify epigenetic modifications in alcohol dependence.Journal of Neuroscience. 32: 1884-1897. Zhang L, Bao Z, Wang S, Hu X _amp; Hu J*. (2008) FISH mapping and identification of Zhikong scallop (Chlamys farreri) chromosomes.Marine Biotechnology.10: 151-157. Zhang L, Bao Z*, Cheng J, Li H, Huang X, Wang S, Zhang C _amp; Hu J. (2007) Fosmid library construction and initial analysis of end sequences in Zhikong scallop (Chlamys farreri).Marine Biotechnology. 9: 606-612. Zhang L, Bao Z*, Wang S, Huang X _amp; Hu J. (2007) Chromosome rearrangements in Pectinidae (Bivalvia: Pteriomorphia) implied based on chromosomal localization of histone H3 gene in four scallops.Genetica. 130: 193-198. 海洋贝类功能基因组学 [海洋信息资源服务平台] → 中国 → 山东 → 青岛 海洋生物医药业;海洋科学研究; 中国海洋大学 博士学位 2018-09-14 18:40:09