刘雅 姓名:刘雅 学历/职称/职务:博士/副教授 邮箱:yaliu @ouc.edu.cn 地址:山东省青岛市鱼山路5号中国海洋大学科学馆210 科研领域:海洋生物医用材料、纳米生物材料 学习工作简历: 2015年12月至今:中国海洋大学 海洋生命学院 副教授 2014年4月_mdash;2015年11月: 中国海洋大学 海洋生命学院 讲师 2012年8月_mdash;2014年1月:国家纳米科学中心 联合培养 2008年9月_mdash;2013年6月:中国海洋大学海洋生命学院 海洋生物学专业 博士 2004年9月_mdash;2008年6月:中国海洋大学海洋生命学院 生物技术专业 学士 代表性成果: 一、承担和参与的课题: 1. 主持,国家自然科学基金,21万,2016.01-2018.12 2. 主持,中国博士后科学基金面上一等资助,8万,2014.9-2016.7 3. 主持,青岛市科技发展计划,5万,2015.9-2017.8 4. 主持,青年教师专项基金,10万,2015.1-2016.12 5.参与,国际合作研究重点项目,94万,2013.4-2016.3 6.参与,国家自然科学基金,85万,2013.1-2016.12 二、近5年发表论文: 1. Ya Liu , Di Zhang , Zeng-Ying Qiao , Guo-Bin Qi , Xing-Jie Liang , Xi-Guang Chen*, Hao Wang*. A Peptide-Network Weaved Nanoplatform with Tumor Microenvironment Responsiveness and Deep Tissue Penetration Capability for Cancer Therapy.Advanced Materials27 (2015) 5034_ndash;5042 2. Ya Liu, Li-Li Li, Guo-Bin Qi, Yun-Shan Fan, Xi-Guang Chen*, Hao Wang*. Dynamic Disordering of Co-Assemblied Liposomal Cocktails: Spatio-Temporal Controlled Release of Cargoes to Circumvent Drug Resistance.Biomaterials 35 (2014) 3406-3415. 3. Ya Liu, Fu-Ping Gao, Di Zhang, Yun-Shan Fan, Xi-Guang Chen*, Hao Wang*. Molecular Structural Transformation Regulated Dynamic Disordering of Supramolecular Vesicles as pH-Responsive Drug Release Systems.Journal of Controlled Release 173 (2014) 140_ndash;147. 4. Ya Liu, Ming Kong, Xiao Jie Cheng, Qian Qian Wang, Li Ming Jiang, Xi Guang Chen*. Self-assembled nanoparticles based on amphiphilic chitosan derivative and hyaluronic acid for gene delivery.Carbohydrate Polymers 94 (2013) 309-316. 5. Ya Liu, Ming Kong, Kui Kun Yang, Yang Li, Jing Su, Xiao Jie Cheng, Hyun Jin Park*, Xi Guang Chen*. Biocompatibility, cellular uptake and biodistribution of the polymeric amphiphilic nanoparticles as oral drug carriers.Colloids and Surfaces B: Biointerfaces 103 (2013) 345-353. 6. Ya Liu, Hui Di Zang, Ming Kong, Fang Kui Ma, Qi Feng Dang, Xiao Jie Cheng*, Qiu Xia Ji, Xi Guang Chen*.In vitroevaluation of mucoadhesion and permeation enhancement of polymeric amphiphilic nanoparticles.Carbohydrate Polymers 89 (2012) 453_ndash; 460. 7. Ya Liu, Xiao Jie Cheng, Qi Feng Dang, Fang Kui Ma,Xi Guang Chen*, Hyun Jin Park, Bum Keun Kim. Preparation and evaluation of Oleoyl-carboxymethy-chitosan (OCMCS) nanoparticles as oral protein carriers.Journal of Material Science: Material in Medicine.23(2012) 375_ndash;384. 8. Zhong Yu Duan,* Yu Juan Gao, Zeng Ying Qiao, Gang Fan, Ya Liu, Di Zhang, and Hao Wang*. A photoacoustic approach for monitoring the drug release of pH-sensitive poly(_beta;-amino ester)s.Journal of Materials Chemistry B2(2014) 6271-6282. 9. Fu-Ping Gao, Yao-Xin Lin, Li-Li Li, Ya Liu, Ulrich Mayerh_ouml;ffer, Peter Spenst, Ji-Guo Su, Jing-Yuan Li*, Frank W_uuml;rthner*, and Hao Wang*. Supramolecular adducts of squaraine and protein for noninvasive tumor imaging and photothermal therapyin vivo.Biomaterials.35 (2014) 1004-1014. 10. Ming Kong*; Lin Hou; Juan Wang; Chao Feng; Ya Liu; Xiao Jie Cheng; Xi Guang Chen*. Enhanced transdermal lymphatic drug delivery of hyaluronic acid modified transfersomes for tumor metastasis therapy.Chemical Communications51(2015) 1453-1456 11. Zeng-Ying Qiao_Dagger;, Di Zhang_Dagger;, Chun-Yuan Hou, Si-Meng Zhao, Ya Liu, Yu-Juan Gao, Ning-Hua Tan* and Hao Wang*. A pH-responsive natural cyclopeptide RA-V drug formulation for improved breast cancer therapy.Journal of Materials Chemistry B.3( 2015) 4514_mdash;4523 12. Zeng-Ying Qiao_Dagger;, Chun-Yuan Hou_Dagger;, Di Zhang, Ya Liu, Yao-Xin Lin, Hong-Wei An, Xiao-Jun Li and Hao Wang*. Self-assembly of cytotoxic peptide conjugated poly(b-amino ester)s for synergistic cancer chemotherapy.Journal of Materials Chemistry B. 3(2015) 2943-2953. 13. Qian Qian Wang; Ming Kong; Yi An; Ya Liu; Jing Jing Li; Xuan Zhou; Jian Li; Shao Yan Jiang; Xiao Jie Cheng*; Xi Guang Chen*. Hydroxybutyl chitosan thermo-sensitive hydrogel: a potential drug delivery system.Journal of Materials Science48(2013)5614-5623. 14. Fang Kui Ma, Jing Li, Ming Kong, Ya Liu, Yi An*, Xi Guang Chen*.Preparation and hydrolytic erosion of differently structured PLGA nanoparticles with chitosan modification.International Journal of Biological Macromolecules 54 (2013) 174_ndash; 179. 15. Kui Kun Yang, Ming Kong, Ya Nan Wei, Ya Liu, Xiao Jie Cheng, Jing Li, Hyun Jin Park*, Xi Guang Chen*. Folate-modified_ndash;chitosan-coated liposomes for tumor-targeted drug delivery.Journal of Material Science (2013)48(4)1717-1728.. 16. Yang Li,Ming Kong,Chao Feng,Wei Fang Liu,Ya Liu,Xiao Jie Cheng*,Xi Guang Chen*. Preparation and property of layer-by-layer alginate hydrogelbeads based on multi-phase emulsion technique.Journal of Sol-Gel Science and Technology 62(2012) 217_ndash;226. 17. Guixue Xia, Xuqian Lang, Ming Kong, Xiaojie Cheng, Ya Liu, Chao Feng, Xiguang Chen*. Surface fluid-swellable chitosan fiber as the wound dressing material.Carbohydrate Polymers 136 (2016) 860_ndash;866 18. Wei Zhao, Ming Kong*, Chao Feng, Xiaojie Cheng, Ya Liu, Xiguang Chen*. Investigation of gelling behavior of thiolated chitosan in alkaline condition and its application in stent coating.Carbohydrate Polymers 136 (2016) 307_ndash;315 19. Juan Wang, Mengxue Xu, Xiaojie Cheng, Ming Kong, Ya Liu, Chao Feng*, Xiguang Chen*. Positive/negative surface charge of chitosan based nanogels and its potential influence on oral insulin delivery.Carbohydrate Polymers 136 (2016) 867_ndash;874 20. Chao Feng*, Jing Li, Ming Kong, Ya Liu, Xiao Jie Cheng, Yang Li, Hyun Jin Park, Xi Guang Chen*. Surface charge effect on mucoadhesion of chitosan based nanogels forlocal anti-colorectal cancer drug delivery.Colloids and Surfaces B: Biointerfaces 128 (2015) 439_ndash;447. 21. Jing Li, Changqing Jiang, Xuqian Lang, Ming Kong, Xiaojie Cheng, Ya Liu, Chao Feng*, Xiguang Chen*. Multilayer sodium alginate beads with porous core containing chitosan based nanoparticles for oral delivery of anticancer drug.International Journal of Biological Macromolecules 85 (2016) 1_ndash;8. 三、专利 1.刘雅,陈西广,程晓杰,孔明,冯超.一种壳寡糖透明质酸复合纳米微粒的制备方法,国家发明专利、申请号20141069938380.2、受理日2014年11月28日 2.陈西广,颜冬,程晓杰,孔明,刘雅.一种H型羧甲基壳聚糖纤维的制备方法,国家发明专利、申请号201410538850.7、受理日2014年10月14日 3.陈西广,朗需谦,程晓杰,孔明,刘雅,冯超.一种海藻酸钠的降解方法,国家发明专利、申请号201510647647.8、受理日2015年10月14日 4.陈西广,王娟,程晓杰,孔明,刘雅,冯超,一种载胰岛素羧甲基壳聚糖-壳聚糖纳米制剂的制备方法,国家发明专利、申请号201510480154.x、受理日2015年8月7日 5.陈西广,王璇璇,程晓杰,孔明,刘雅,冯超.一种岩藻黄素微胶囊的制备方法,国家发明专利、申请号201610059392.8、受理日2016年2月1日 海洋生物医用材料;纳米生物材料 [海洋信息资源服务平台] → 中国 涉海产品及材料制造业;海洋生物医药业; 中国海洋大学 博士学位 2022-01-13 09:58:11 2018-08-23 19:42:09